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Sexually transmitted infections situation is a cause for concern in Poland

Iwona Rudnicka and Slawomir Majewski

Instytut Wenerologii Akademii Medycznej w Warszawie (Institute of Venerology, Medical Academy of Warsaw), Warsaw, Poland

Public health surveillance of sexually transmitted infections (STIs) began in Poland in 1946, in response to an epidemic of syphilis and gonorrhoea that occurred after the second world war [1]. The system established included reporting and registration of cases, partner notification and treatment, and the screening of pregnant women for syphilis. This system existed until 2001, when the new Infectious Diseases and Infections law was passed [2]. The new list of notifiable STIs includes syphilis, gonorrhoea, non-gonoccoccal urethritis, genital herpes, genital warts, and HIV. HIV surveillance is carried out separately by the Panstwowy Zaklad Higeny (National Institute of Hygiene).

National STI surveillance in Poland relies on both laboratory and physician reporting (Table 1). Local dermato-venereological clinics report data to the regional Register of Venereal Diseases, which sends annual aggregated reports to the Instytut Wenerologii (Institute of Venereology) in Warsaw. The Institute monitors the national epidemiological situation and publishes an annual analysis of trends.

Table 1. General information on STI surveillance system in Poland

Public health surveillance includes:

  • Individual notification of syphilis, gonorrhoea, non-gonoccoccal urethritis (NGU), genital herpes and genital warts cases by all clinicians
  • Reporting of positive or equivocal results of tests for these diseases by all laboratories
  • Contact tracing and prophylactic treatment of sexual partners
  • Testing for syphilis of all pregnant women (twice during pregnancy)
  • Follow-up and treatment of newborns delivered by women with syphilis
Physician diagnosing STI is obliged to:
  • Start treatment immediately
  • Advise the patient to notify sexual partners: the source of infection and those exposed to infection and/or offer the clinic’s help in notifying the partners
  • Examine and treat the above mentioned patients, including those without symptoms (prophylactic treatment)
  • Report the case to the Register of Venereal Diseases Laboratories
  • All positive results of serological or microbiological laboratory investigations confirmatory for STI must be reported by the laboratories to the Register of Venereal Diseases

Results
Syphilis

Recorded syphilis incidence has decreased in recent years (Figure 1). In 2003, 982 cases of syphilis were registered, and the incidence (2.02/100 000 population) was 16% lower than in 2002. There was a 19% decrease in primary syphilis incidence and 14% decrease in early latent syphilis incidence in 2003. The rate of secondary syphilis (0.52/100 000) remained stable. Syphilis was diagnosed in 55 women during pregnancy or delivery (72 women in 2002).

In 2003, congenital syphilis was diagnosed in 13 children aged 1 to 12 years. The congenital syphilis rate per 1000 live births peaked in 2002 (0.0452 per 1000 live births), and in 2003, this rate was still high (Figure 1).

This fall in recorded syphilis should be seen in the context of a decline in testing. In 2003, 941 932 blood samples were tested for syphilis by the network of venereology laboratories. This number for 2003 was 19% less than in 2002, about 65% lower than the number of tests in performed in 1999, and 89% less than the number of tests done in 1990 (Table 4).

The index of immediate treatment of contact persons to cases increased from 0.19 in 2002 to 0.27 in 2003. This index is calculated as the ratio of the number of individuals treated by prophylaxis to the number of all primary syphilis cases.

Figure 1. Distribution of reported syphilis cases and syphilis incidence by stage of infection, Poland 1999 – 2003.

Table 3. Incidence of congenital syphilis and syphilis diagnosed in pregnancy and childbirth

Year Syphilis
(total cases)
Congenital syphilis Congenital syphilis: rate per 1000 live births Syphilis in pregnancy/ delivery Syphilis in pregnancy / delivery: rate per 1000 live births Number of live births
1990 2054 4 0.0073 75 0.14 547 700
1995 1565 10 0.023 88 0.20 433 100
1999 1061 10 0.026 49 0.13 382 000
2000 968 7 0.019 39 0.10 378 300
2001 1057 10 0.027 57 0.15 368 200
2002 1194 16 0.045 72 0.20 353 800
2003 969 13 0.037 55 0.16 351 100


Table 4.Testing for syphilis by the network of venereology laboratories

Year Number of syphilis tests Syphilis - total
1990 8 218 674 2054
1995 6 455 102 1565
1999 2 701 861 1061
2000 1 253 135 968
2001 1 409 611 1057
2002 1 157 979 1194
2003 941 932 969

Other STIs
There were 670 cases of gonorrhoea reported in 2003. This was an increase of 11% from 2002. The index of immediate treatment of contact persons increased from 0.09 in 2002 to 0.12 in 2003.

The registered incidence of other STIs decreased in 2003. The incidence of non-gonococcal urethritis decreased by 13%, genital warts by 10%, and genital herpes by 27% (Figure 2).

Figure 2. Sexually transmitted infections in Poland, 1990 - 2003. [4,5]

Discussion and conclusions
Several alarming trends persisted in 2003. Firstly, the number of syphilis tests performed has dropped dramatically since the 1990s (Table 4). Secondly, the proportion of contacts of syphilis or gonorrhoea patients treated immediately continues to be low. Thirdly, it is worrying that there has been no decrease in women diagnosed with syphilis during pregnancy, despite large decreases in rates of testing. Congenital syphilis rates increased in the early 1990’s and have remained at a higher level to 2003.

Since diagnosis of early latent and secondary syphilis cases relies on laboratory investigations, these cases may be underdiagnosed. Unsatisfactory detection of early latent syphilis is also related to the limiting of the syphilis screening program to blood donors and pregnant women. Before 2001, the screened population included all patients in hospital, those employed in the healthcare and education systems, food industry workers, first time employed and prisoners. Moreover, although every pregnant woman should be screened for syphilis twice during her pregnancy under current regulations, this is not always the case, and the rate of congenital syphilis is rising (Table 3).

There is inadequate financing to maintain a functional surveillance system with appropriate laboratory screening and health promotion activities. Furthermore, effective contact tracing and notification of cases by physicians are sometimes hampered by misinterpretation of the legal regulations and fear of breaching the Data Protection Act. In addition to the unfavourable circumstances in the healthcare system, the STI epidemiological situation is affected by increasing numbers of commercial sex workers (both brothels and street prostitution) and an exceptional growth of syphilis and HIV/AIDS incidence in the bordering Newly Independent States.

Treatment and testing for STI patients was government funded until 2001, and were free of charge for all patients. Since 2001, STI treatment has been financed by public healthcare insurance, which covers only employed persons and their families, the retired and pensioners, and, for a limited time, registered unemployed persons. Even people who have insurance must pay part of the medication costs.

In order to control the STIs in Poland, it is now crucial that free treatment be provided for all STI patients, regardless of whether or not they are insured. If there is an STI epidemic, which could well happen in Poland and eastern European countries, costs of treatment are likely to be much higher than the costs of effective prevention.

Footnote: Syphilis case definitions used in Poland

Case definition for Primary Syphilis.
Primary ulcer (or other clinical manifestations) with regional lymphadenopathy confirmed by positive dark-field microscopy and/or positive serological tests: USR/VDRL/RPR and FTA-ABS, FTA.

Case definition for Secondary Syphilis
Polymorphic skin eruptions, mucosal eruptions, alopecia, generalised lymphadenopathy confirmed by positive serological tests USR/VDRL/RPR and FTA-ABS, FTA.

Case definition for All Syphilis
If early acquired symptomatic (primary, secondary - as above), if late acquired symptomatic - confirmed by neurologist, psychiatrist, cardiologist, radiologist etc. Serological tests - in all symptomatic and asymptomatic cases.

Case definition for Congenital Syphilis
Clinical changes in stillbirth delivered by syphilitic mothers; clinical changes typical for early and late congenital syphilis with positive serological tests; positive serological tests persisting for longer then 6 months (USR) and 12 months (FTA) and if possible IgM tests.

References:
  1. Towpik J. [Sexually transmited diseases] in Infectious Diseases in Poland and their control in 1961-1970. Ed. Jan Kostrzewski; PZWL, Warsaw 1973.
  2. Ustawa o chorobach zakaznych i zakazeniachz dnia 6 wrzesnia 2001. Dz. U Nr 126 poz. 1384 (http://isip.sejm.gov.pl/prawo/index.html) (6.09.2001, Dz.U. Nr 126, poz. 1384)
  3. Rudnicka I, Popielarski M, Majewski S. Rola Instytutu Wenerologii w zwalczaniu AIDS. Seksuologia 1998; 5:10-14.
  4. Majewski S, Rudnicka I, Zielinski H. Sytuacja epidemiologiczna w 1999 roku w zakresie chorób przenoszonych droga plciowa. Przeg Derm 87:529-532, 2000
  5. Pniewski T, Majewski S. Prevalence of syphilis in Poland. CEDVA Bull 2000; 2:24-25.

Источник: Eurosurveillance weekly releases 2005 > Volume 10 / Issue 2


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